TERF1 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TERF1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human TERF1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Ammonium sulfate precipitation
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of TERF1 polyclonal antibody (Cat # PAB2607) in Jurkat cell line lysates (35 ug/lane). TERF1 (C-term) (arrow) was detected using the purified polyclonal antibody. -
Gene Info — TERF1
Entrez GeneID
7013Gene Name
TERF1
Gene Alias
FLJ41416, PIN2, TRBF1, TRF, TRF1, hTRF1-AS, t-TRF1
Gene Description
telomeric repeat binding factor (NIMA-interacting) 1
Omim ID
600951Gene Ontology
HyperlinkGene Summary
This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq
Other Designations
telomeric repeat binding factor 1|telomeric repeat binding protein 1
-
Interactome
-
Disease
-
Publication Reference
-
Regulation of telomeric repeat binding factor 1 binding to telomeres by casein kinase 2-mediated phosphorylation.
Kim MK, Kang MR, Nam HW, Bae YS, Kim YS, Chung IK.
The Journal of Biological Chemistry 2008 May; 283(20):14144.
Application:IF, WB, Human, MCF-7 cells.
-
Tethering telomeric double- and single-stranded DNA-binding proteins inhibits telomere elongation.
Etheridge KT, Compton SA, Barrientos KS, Ozgur S, Griffith JD, Counter CM.
The Journal of Biological Chemistry 2008 Mar; 283(11):6935.
-
Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation.
Muramatsu Y, Tahara H, Ono T, Tsuruo T, Seimiya H.
Experimental Cell Research 2008 Mar; 314(5):1115.
-
Regulation of telomeric repeat binding factor 1 binding to telomeres by casein kinase 2-mediated phosphorylation.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com