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Last updated: 2017/6/25

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SCN1A polyclonal antibody

  • Catalog # : PAB26052
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of SCN1A.
  • Immunogen:
  • A synthetic peptide corresponding to 16 amino acids at N-terminus of human SCN1A.
  • Host:
  • Rabbit
  • Reactivity:
  • Chicken, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
  • Specificity:
  • BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SCN2A (100%), SCN3A (94%).
  • Form:
  • Liquid
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of human brain, cerebellum with SCN1A polyclonal antibody (Cat # PAB26052).
    Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6323
  • Gene Name:
  • SCN1A
  • Gene Alias:
  • FEB3,GEFSP2,HBSCI,NAC1,Nav1.1,SCN1,SMEI
  • Gene Description:
  • sodium channel, voltage-gated, type I, alpha subunit
  • Gene Summary:
  • The vertebrate sodium channel is a voltage-gated ion channel essential for the generation and propagation of action potentials, mainly in nerve and muscle. Voltage-sensitive sodium channels are heteromeric complexes consisting of a large central pore-forming glycosylated alpha subunit, and two smaller auxiliary beta subunits. This gene encodes the large alpha subunit, and mutations in this gene have been associated with several epilepsy, convulsion and migraine disorders
  • Other Designations:
  • febrile convulsions 3,sodium channel protein, brain I alpha subunit,sodium channel, voltage-gated, type I, alpha,sodium channel, voltage-gated, type I, alpha polypeptide
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