P2RY12 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of P2RY12.
Immunogen
A synthetic peptide corresponding to 17 amino acids at N-terminus of human P2RY12.
Host
Rabbit
Reactivity
Human
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (32 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human blood, platelets with P2RY12 polyclonal antibody (Cat # PAB26005).
Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.Immunocytochemistry
Immunocytochemical staining of HEK293 human embryonic kidney cells transfected with P2RY12. Primary antibody using P2RY12 polyclonal antibody (Cat # PAB26005). -
Gene Info — P2RY12
Entrez GeneID
64805Protein Accession#
Q9H244Gene Name
P2RY12
Gene Alias
ADPG-R, HORK3, P2T(AC), P2Y(AC), P2Y(ADP), P2Y(cyc), P2Y12, SP1999
Gene Description
purinergic receptor P2Y, G-protein coupled, 12
Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene. [provided by RefSeq
Other Designations
ADP-glucose receptor|G-protein coupled receptor SP1999|Gi-coupled ADP receptor HORK3|P2Y purinoceptor 12|platelet ADP receptor|purinergic receptor P2RY12|purinergic receptor P2Y12|putative G-protein coupled receptor
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Interactome
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Disease
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