PPAT polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of PPAT polyclonal antibody (Cat # PAB2598) in HepG2 cell line lysates (35 ug/lane).PPAT (arrow) was detected using the purified polyclonal antibody.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PPAT.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to internal region of human PPAT.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Ammonium sulfate precipitation
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of PPAT polyclonal antibody (Cat # PAB2598) in HepG2 cell line lysates (35 ug/lane).PPAT (arrow) was detected using the purified polyclonal antibody. -
Gene Info — PPAT
Entrez GeneID
5471Protein Accession#
NP_002694;Q06203Gene Name
PPAT
Gene Alias
ATASE, GPAT, PRAT
Gene Description
phosphoribosyl pyrophosphate amidotransferase
Omim ID
172450Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. This protein is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. This gene and PAICS/AIRC, a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway, are located in close proximity on chromosome 4. [provided by RefSeq
Other Designations
amidophosphoribosyltransferase|glutamine PRPP amidotransferase|glutamine phosphoribosylpyrophosphatate amidotransferase
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Interactome
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Pathway
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Publication Reference
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Interdomain signaling in glutamine phosphoribosylpyrophosphate amidotransferase.
Bera AK, Chen S, Smith JL, Zalkin H.
The Journal of Biological Chemistry 1999 Dec; 274(51):36498.
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Assignment of the gene for phosphoribosylpyrophosphate amidotransferase to the pter leads to q21 region of human chromosome 4.
W Stanley, E H Chu.
Cytogenetics and Cell Genetics 1978 Jan; 22(1-6):228.
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Interdomain signaling in glutamine phosphoribosylpyrophosphate amidotransferase.
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