LPHN2 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of LPHN2.
Immunogen
A synthetic peptide corresponding to 16 amino acids at N-terminus of human LPHN2.
Host
Rabbit
Reactivity
Human
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (18-45 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human brain, neurons and glia with LPHN2 polyclonal antibody (Cat # PAB25949).
Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. -
Gene Info — LPHN2
Entrez GeneID
23266Protein Accession#
O95490Gene Name
LPHN2
Gene Alias
CIRL2, CL2, LEC1, LPHH1
Gene Description
latrophilin 2
Omim ID
607018Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. While several transcript variants have been described, the biological validity of only one has been determined. [provided by RefSeq
Other Designations
OTTHUMP00000011441|OTTHUMP00000011444|calcium-independent alpha-latrotoxin receptor 2|latrophilin 1|latrophilin homolog 1|latrophilin homolog 2 (cow)|lectomedin-1
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