CFL1 (phospho Y139) polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using CFL1 (phospho Y139) polyclonal antibody (Cat # PAB25900).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of CFL1.
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding Y139 of human CFL1.
Sequence
N-C-Yp-E-E
Host
Rabbit
Theoretical MW (kDa)
19
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity chromatography
Concentration
1 mg/mL
Recommend Usage
Immunohistochemistry (1:50-1:100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using CFL1 (phospho Y139) polyclonal antibody (Cat # PAB25900). -
Gene Info — CFL1
Entrez GeneID
1072Protein Accession#
P23528Gene Name
CFL1
Gene Alias
CFL
Gene Description
cofilin 1 (non-muscle)
Omim ID
601442Gene Ontology
HyperlinkGene Summary
Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM
Other Designations
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Interactome
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Pathway
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Disease
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