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Last updated: 2016/11/27
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SNCA (phospho Y133) polyclonal antibody

  • Catalog # : PAB25866
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of SNCA.
  • Immunogen:
  • Synthetic phosphopeptide corresponding to residues surrounding Y133 of human SNCA.
  • Sequence:
  • E-G-YpQ-D
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 18
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity chromatography
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Immunofluorescence (1:100-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of methanol-fixed HeLa cells using SNCA (phospho Y133) polyclonal antibody (Cat # PAB25866, red).
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 6622
  • Gene Name:
  • SNCA
  • Gene Alias:
  • MGC110988,NACP,PARK1,PARK4,PD1
  • Gene Description:
  • synuclein, alpha (non A4 component of amyloid precursor)
  • Gene Summary:
  • Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000161559,OTTHUMP00000161561,alpha synuclein,alpha-synuclein,alpha-synuclein, isoform NACP140,non A-beta component of AD amyloid,non A4 component of amyloid
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