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NKX2-6 polyclonal antibody

  • Catalog # : PAB25800
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of NKX2-6.
  • Immunogen:
  • A synthetic peptide corresponding to 15 amino acids at internal region of human NKX2-6.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • NKX2-6 antibody is predicted to not cross-react with other NK2 homeobox family members. At least two isoforms of NKX2-6 are known to exist; this antibody will detect both isoforms.
  • Form:
  • Liquid
  • Purification:
  • Peptide affinity purification
  • Concentration:
  • 1 mg/mL
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    Immunohistochemistry (5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of NKX2-6 in mouse spleen tissue with NKX2-6 polyclonal antibody (Cat # PAB25800) at 1 ug/mL in (lane 1) the absence and (lane 2) the presence of blocking peptide.
  • Immunohistochemistry
  • Immunohistochemistry
  • Immunohistochemical analysis of NKX2-6 in human spleen tissue with NKX2-6 polyclonal antibody (Cat # PAB25800) at 5 ug/mL.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • NKX2-6
  • Gene Alias:
  • CSX2,NKX4-2
  • Gene Description:
  • NK2 transcription factor related, locus 6 (Drosophila)
  • Gene Summary:
  • Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development (Shiojima et al., 1995 [PubMed 7665173]). It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is essential for development of the heart-like dorsal vessel. NKX2-6 is a vertebrate homolog of 'tinman' (Newman and Krieg, 1998 [PubMed 9621430]).[supplied by OMIM
  • Other Designations:
  • NK2 transcription factor related, locus 6,tinman paralog
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