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Last updated: 2017/3/19
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GRB10 polyclonal antibody

  • Catalog # : PAB25795
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of GRB10.
  • Immunogen:
  • A synthetic peptide corresponding to 17 amino acids at C-terminus of human GRB10.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • At least three isoforms of GRB10 are known to exist; this antibody will detect all three isoforms.
  • Form:
  • Liquid
  • Purification:
  • Peptide affinity purification
  • Concentration:
  • 1 mg/mL
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1-2 ug/mL)
    Immunofluorescence (20 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of GRB10 in SK-N-SH cell lysate with GRB10 polyclonal antibody (Cat # PAB25795) at (lane 1) 1 and (lane 2) 2 ug/mL.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence analysis of GRB10 in rat brain with GRB10 polyclonal antibody (Cat # PAB25795) at 20 ug/mL.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2887
  • Gene Name:
  • GRB10
  • Gene Alias:
  • GRB-IR,Grb-10,IRBP,KIAA0207,MEG1,RSS
  • Gene Description:
  • growth factor receptor-bound protein 10
  • Gene Summary:
  • The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
  • Other Designations:
  • GRB10 adaptor protein,insulin receptor-binding protein Grb-IR,maternally expressed gene 1
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