KPNA5 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of KPNA5.
Immunogen
A synthetic peptide corresponding to 18 amino acids at N-terminus of human KPNA5.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
KPNA5 antibody is predicted to not cross-react with other Importin alpha family members.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
Immunocytochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of KPNA5 in EL4 cell lysate with KPNA5 polyclonal antibody (Cat # PAB25781) at 1 ug/mL in (lane 1) the absence and (lane 2) the presence of blocking peptide.Immunocytochemistry
Immunocytochemical anyalysis of KPNA5 in EL4 cell lysate with KPNA5 polyclonal antibody (Cat # PAB25781) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — KPNA5
Entrez GeneID
3841Protein Accession#
CAH71948Gene Name
KPNA5
Gene Alias
IPOA6, SRP6
Gene Description
karyopherin alpha 5 (importin alpha 6)
Omim ID
604545Gene Ontology
HyperlinkGene Summary
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA5 protein belongs to the importin alpha protein family and is thought to be involved in NLS-dependent protein import into the nucleus. [provided by RefSeq
Other Designations
OTTHUMP00000017076|importin alpha 6|karyopherin alpha 5
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