DISP1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DISP1.
Immunogen
A synthetic peptide corresponding to 16 amino acids at N-terminus of human DISP1.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
At least two isoforms of DISP1 are known to exist; this antibody will detect both isoforms. DISP1 antibody is predicted to not cross-react with EMX1.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of DISP1 in NIH/3T3 cell lysate with DISP1 polyclonal antibody (Cat # PAB25755) at 1 ug/mL.Immunohistochemistry
Immunohistochemical analysis of DISP1 in human kidney tissue with DISP1 polyclonal antibody (Cat # PAB25755) at 2.5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — DISP1
Entrez GeneID
84976Protein Accession#
NP_116279Gene Name
DISP1
Gene Alias
DISPA, DKFZp434I0428, FLJ43740, MGC104180, MGC13130, MGC16796
Gene Description
dispatched homolog 1 (Drosophila)
Omim ID
607502Gene Ontology
HyperlinkGene Summary
The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq
Other Designations
OTTHUMP00000036011|dispatched A
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