PRICKLE1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of PRICKLE1 in human bladder tissue with PRICKLE1 polyclonal antibody (Cat # PAB25745) at 1 ug/mL.
Immunofluorescence
Immunofluorescence analysis of PRICKLE1 in human bladder with PRICKLE1 polyclonal antibody (Cat # PAB25745) at 20 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PRICKLE1.
Immunogen
A synthetic peptide corresponding to 19 amino acids at C-terminus of human PRICKLE1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
Multiple isoforms of PRICKLE1 are known to exist. PRICKLE1 antibody is predicted to not cross-react with other PRICKLE protein family members.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
Immunofluorescence (20 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of PRICKLE1 in human bladder tissue with PRICKLE1 polyclonal antibody (Cat # PAB25745) at 1 ug/mL.Immunofluorescence
Immunofluorescence analysis of PRICKLE1 in human bladder with PRICKLE1 polyclonal antibody (Cat # PAB25745) at 20 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PRICKLE1
Entrez GeneID
144165Protein Accession#
NP_694571Gene Name
PRICKLE1
Gene Alias
EPM1B, FLJ31627, FLJ31937, MGC138902, MGC138903, RILP
Gene Description
prickle homolog 1 (Drosophila)
Omim ID
608500Gene Ontology
HyperlinkGene Summary
This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq
Other Designations
REST (RE-1 silencing transcription factor)/NRSF (neuron-restrictive silencer factor)-interacting LIM domain protein|REST/NRSF-interacting LIM domain protein|prickle-like 1
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Interactome
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Pathway
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Disease
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