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UPK1B polyclonal antibody

  • Catalog # : PAB25730
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of UPK1B.
  • Immunogen:
  • A synthetic peptide corresponding to 17 amino acids at internal region of human UPK1B.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • At least two isoforms of UPK1B are known to exist; this antibody will recognize both isoforms. UPK1B antibody is predicted to not cross-react with other tetraspanin protein family members.
  • Form:
  • Liquid
  • Purification:
  • Peptide affinity purification
  • Concentration:
  • 1 mg/mL
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (0.5-1 ug/mL)
    Immunohistochemistry (5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of UPK1B in mouse bladder tissue with UPK1B polyclonal antibody (Cat # PAB25730) at 0.5 ug/mL in (lane 1) the absence and (lane 2) the presence of blocking peptide.
  • Immunohistochemistry
  • Immunohistochemistry
  • Immunohistochemical analysis of UPK1B in human bladder tissue with UPK1B polyclonal antibody (Cat # PAB25730) at 5 ug/mL.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7348
  • Gene Name:
  • UPK1B
  • Gene Alias:
  • TSPAN20,UPIB,UPK1
  • Gene Description:
  • uroplakin 1B
  • Gene Summary:
  • The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq
  • Other Designations:
  • tetraspan
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