EI24 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of EI24 in rat liver tissue with EI24 polyclonal antibody (Cat # PAB25726) at (lane 1) 1 and (lane 2) 2 ug/mL.
Immunohistochemistry
Immunohistochemical analysis of EI24 in rat liver tissue with EI24 polyclonal antibody (Cat # PAB25726) at 5 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of EI24.
Immunogen
A synthetic peptide corresponding to 19 amino acids at C-terminus of human EI24.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
At least two isoforms of EI24 are known to exist; this antibody will only detect the larger isoform.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of EI24 in rat liver tissue with EI24 polyclonal antibody (Cat # PAB25726) at (lane 1) 1 and (lane 2) 2 ug/mL.Immunohistochemistry
Immunohistochemical analysis of EI24 in rat liver tissue with EI24 polyclonal antibody (Cat # PAB25726) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — EI24
Entrez GeneID
9538Protein Accession#
NP_004870Gene Name
EI24
Gene Alias
PIG8, TP53I8
Gene Description
etoposide induced 2.4 mRNA
Omim ID
605170Gene Ontology
HyperlinkGene Summary
This gene has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The protein encoded by this gene contains six putative transmembrane domains and may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
etoposide induced 2.4|tumor protein p53 inducible protein 8
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Interactome
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