SEC62 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of SEC62 in rat brain tissue with SEC62 polyclonal antibody (Cat # PAB25722) at (lane 1) 0.5 and (lane 2) 1 ug/mL.
Immunohistochemistry
Immunohistochemical analysis of SEC62 in mouse brain tissue with SEC62 polyclonal antibody (Cat # PAB25722) at 5 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SEC62.
Immunogen
A synthetic peptide corresponding to 18 amino acids at C-terminus of human SEC62.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
SEC62 antibody is predicted to not cross-react with other SEC proteins. Multiple isoforms of SEC62 are known to exist.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (0.5-1 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of SEC62 in rat brain tissue with SEC62 polyclonal antibody (Cat # PAB25722) at (lane 1) 0.5 and (lane 2) 1 ug/mL.Immunohistochemistry
Immunohistochemical analysis of SEC62 in mouse brain tissue with SEC62 polyclonal antibody (Cat # PAB25722) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SEC62
Entrez GeneID
7095Protein Accession#
NP_003253Gene Name
SEC62
Gene Alias
Dtrp1, FLJ32803, HTP1, TLOC1, TP-1
Gene Description
SEC62 homolog (S. cerevisiae)
Omim ID
602173Gene Ontology
HyperlinkGene Summary
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq
Other Designations
membrane protein SEC62, S.cerevisiae, homolog of|translocation protein 1|translocation protein SEC62
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