FXYD7 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FXYD7.
Immunogen
A synthetic peptide corresponding to 17 amino acids at N-terminus of human FXYD7.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
FXYD7 antibody is human, mouse and rat reactive. FXYDY7 antibody is predicted to not react with other members of the FXDY protein family.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
Immunohistochemistry (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of FXYD7 in human lung tissue with FXYD7 polyclonal antibody (Cat # PAB25720) at 1 ug/mL.Immunohistochemistry
Immunohistochemical analysis of FXYD7 in rat lung tissue with FXYD7 polyclonal antibody (Cat # PAB25720) at 2.5 ug/mL.Immunofluorescence
Immunofluorescence analysis of FXYD7 in rat lung tissue with FXYD7 polyclonal antibody (Cat # PAB25720) at 20 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — FXYD7
Entrez GeneID
53822Protein Accession#
AAH18619Gene Name
FXYD7
Gene Alias
FLJ25096
Gene Description
FXYD domain containing ion transport regulator 7
Omim ID
606684Gene Ontology
HyperlinkGene Summary
This reference sequence was derived from multiple replicate ESTs and validated by similar human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. This gene product, FXYD7, is novel and has not been characterized as a protein. [RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu.
Other Designations
FXYD domain-containing ion transport regulator 7
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