TLR8 polyclonal antibody
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More Files
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Immunohistochemistry
Immunohistochemical analysis of TLR8 in human thymus tissue with TLR8 polyclonal antibody (Cat # PAB25701) at 5 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TLR8.
Immunogen
A synthetic peptide corresponding to 15 amino acids at C-terminus of human TLR8.
Host
Rabbit
Reactivity
Human
Specificity
At least three isoforms of TLR8 are known to exist. TLR8 antibody is predicted to not cross-react with other TLR protein family members.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemical analysis of TLR8 in human thymus tissue with TLR8 polyclonal antibody (Cat # PAB25701) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TLR8
Entrez GeneID
51311Protein Accession#
NP_619542Gene Name
TLR8
Gene Alias
CD288, MGC119599, MGC119600
Gene Description
toll-like receptor 8
Omim ID
300366Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq
Other Designations
OTTHUMP00000022930
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Interactome
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Pathway
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Disease
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