WIPI2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of WIPI2.
Immunogen
A synthetic peptide corresponding to 17 amino acids at N-terminus of human WIPI2.
Host
Rabbit
Theoretical MW (kDa)
50
Reactivity
Human, Rat
Specificity
WIPI2 antibody is human and rat reactive. Multiple isoforms of WIPI2 are known to exist. WIPI2 antibody is predicted to not cross-react with WIPI1.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of WIPI2 in human testis tissue with WIPI2 polyclonal antibody (Cat # PAB25670) at 1 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — WIPI2
Entrez GeneID
26100Protein Accession#
NP_056425Gene Name
WIPI2
Gene Alias
Atg21, CGI-50, DKFZp434J154, DKFZp686P02188, FLJ12979, FLJ14217, FLJ42984, WIPI-2
Gene Description
WD repeat domain, phosphoinositide interacting 2
Omim ID
609225Gene Ontology
HyperlinkGene Summary
WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM
Other Designations
WD40 repeat protein interacting with phosphoinositides 2|WIPI49-like protein 2
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