APBA1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of APBA1 in rat brain tissue with APBA1 polyclonal antibody (Cat # PAB25658) at 0.5 ug/ml in (1) the absence and (2) the presence of blocking peptide.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of APBA1.
Immunogen
A synthetic peptide corresponding to 19 amino acids at N-terminus of human APBA1.
Host
Rabbit
Theoretical MW (kDa)
92
Reactivity
Human, Mouse, Rat
Specificity
At least two alternatively spliced isoforms are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with other APBA proteins.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (0.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of APBA1 in rat brain tissue with APBA1 polyclonal antibody (Cat # PAB25658) at 0.5 ug/ml in (1) the absence and (2) the presence of blocking peptide.Enzyme-linked Immunoabsorbent Assay
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Gene Info — APBA1
Entrez GeneID
320Protein Accession#
NP_001154Gene Name
APBA1
Gene Alias
D9S411E, MINT1, X11, X11A, X11ALPHA
Gene Description
amyloid beta (A4) precursor protein-binding, family A, member 1
Omim ID
602414Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq
Other Designations
OTTHUMP00000021438|adaptor protein X11alpha|amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)|amyloid beta A4 precursor protein-binding, family A, member 1|neuron-specific X11 protein|neuronal munc18-1-interacting protein 1|phosphotyro
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Interactome
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Disease
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