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TCIRG1 polyclonal antibody

  • Catalog # : PAB25649
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of TCIRG1.
  • Immunogen:
  • A synthetic peptide corresponding to 19 amino acids at N-terminus of human TCIRG1.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 91
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • At least two alternatively spliced isoforms are known to exist; this antibody will only detect the larger isoform.
  • Form:
  • Liquid
  • Purification:
  • Peptide affinity purification
  • Concentration:
  • 1 mg/mL
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (0.5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of TCIRG1 in EL4 cell lysate with TCIRG1 polyclonal antibody (Cat # PAB25649) at 0.5 ug/ml in (1) the absence and (2) the presence of blocking peptide.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • TCIRG1
  • Gene Alias:
  • ATP6N1C,ATP6V0A3,Atp6i,OC-116kDa,OC116,OPTB1,Stv1,TIRC7,Vph1,a3
  • Gene Description:
  • T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
  • Gene Summary:
  • Through alternate splicing, this gene encodes two proteins with similarity to subunits of the vacuolar ATPase (V-ATPase) but the encoded proteins seem to have different functions. V-ATPase is a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Mutations in this gene are associated with infantile malignant osteopetrosis. [provided by RefSeq
  • Other Designations:
  • ATPase, H+ transporting, 116kD,T cell immune response cDNA7 protein,T-cell immune regulator 1,T-cell, immune regulator 1,T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3,T-cell, immune regulator 1, ATPase, H+ transporting, lyso
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