BCAR3 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of BCAR3 in mouse kidney tissue with BCAR3 polyclonal antibody (Cat # PAB25641) at (1) 1 and (2) 2 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of BCAR3.
Immunogen
A synthetic peptide corresponding to 16 amino acids at N-terminus of human BCAR3.
Host
Rabbit
Theoretical MW (kDa)
91
Reactivity
Human, Mouse, Rat
Specificity
At least four isoforms of BCAR3 are known to exist; this antibody will only recognize the largest isoform. BCAR3 antibody is predicted to not cross-react with other BCAR proteins.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of BCAR3 in mouse kidney tissue with BCAR3 polyclonal antibody (Cat # PAB25641) at (1) 1 and (2) 2 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — BCAR3
Entrez GeneID
8412Protein Accession#
NP_003558Gene Name
BCAR3
Gene Alias
KIAA0554, NSP2, SH2D3B
Gene Description
breast cancer anti-estrogen resistance 3
Omim ID
604704Gene Ontology
HyperlinkGene Summary
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. [provided by RefSeq
Other Designations
OTTHUMP00000011959|OTTHUMP00000011960|OTTHUMP00000011961|breast cancer antiestrogen resistance 3|dJ1033H22.2 (breast cancer anti-estrogen resistance 3)
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Interactome
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Disease
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