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BCAR3 polyclonal antibody

  • Catalog # : PAB25641
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of BCAR3.
  • Immunogen:
  • A synthetic peptide corresponding to 16 amino acids at N-terminus of human BCAR3.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 91
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • At least four isoforms of BCAR3 are known to exist; this antibody will only recognize the largest isoform. BCAR3 antibody is predicted to not cross-react with other BCAR proteins.
  • Form:
  • Liquid
  • Purification:
  • Peptide affinity purification
  • Concentration:
  • 1 mg/mL
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of BCAR3 in mouse kidney tissue with BCAR3 polyclonal antibody (Cat # PAB25641) at (1) 1 and (2) 2 ug/mL.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8412
  • Gene Name:
  • BCAR3
  • Gene Alias:
  • KIAA0554,NSP2,SH2D3B
  • Gene Description:
  • breast cancer anti-estrogen resistance 3
  • Gene Summary:
  • Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000011959,OTTHUMP00000011960,OTTHUMP00000011961,breast cancer antiestrogen resistance 3,dJ1033H22.2 (breast cancer anti-estrogen resistance 3)
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