WIPI1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of WIPI1.
Immunogen
A synthetic peptide corresponding to 17 amino acids at C-terminus of human WIPI1.
Host
Rabbit
Theoretical MW (kDa)
49
Reactivity
Human, Mouse, Rat
Specificity
At least two isoforms of WIPI1 are known to exist; this antibody will detect both isoforms.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of WIPI1 in rat colon tissue with WIPI1 polyclonal antibody (Cat # PAB25622) at (1) 1 and (2) 2 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — WIPI1
Entrez GeneID
55062Protein Accession#
NP_060453Gene Name
WIPI1
Gene Alias
ATG18, FLJ10055, WIPI49
Gene Description
WD repeat domain, phosphoinositide interacting 1
Omim ID
609224Gene Ontology
HyperlinkGene Summary
WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI1, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM
Other Designations
WD40 repeat protein Interacting with phosphoInositides of 49kDa|WIPI-1 alpha
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