ZIC4 polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of ZIC4 (arrow) using rabbit ZIC4 polyclonal antibody (Cat # PAB2562). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ZIC4 gene (Lane 2) (Origene Technologies).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ZIC4.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to amino acids 305-334 at C-terminus of human ZIC4.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of ZIC4 (arrow) using rabbit ZIC4 polyclonal antibody (Cat # PAB2562). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ZIC4 gene (Lane 2) (Origene Technologies). -
Gene Info — ZIC4
Entrez GeneID
84107Protein Accession#
NP_115529;Q8N9L1Gene Name
ZIC4
Gene Alias
FLJ42609, FLJ45833
Gene Description
Zic family member 4
Omim ID
608948Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 1, a related family member on chromosome 3. This gene encodes a protein of unknown function. [provided by RefSeq
Other Designations
zinc family member 4 protein HZIC4|zinc finger protein of the cerebellum 4
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Publication Reference
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Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family.
Ishiguro A, Inoue T, Mikoshiba K, Aruga J.
Biochemical and Biophysical Research Communications 2004 Nov; 324(1):302.
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Heterozygous deletion of the linked genes ZIC1 and ZIC4 is involved in Dandy-Walker malformation.
Grinberg I, Northrup H, Ardinger H, Prasad C, Dobyns WB, Millen KJ.
Nature Genetics 2004 Oct; 36(10):1053.
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Identification and characterization of Zic4, a new member of the mouse Zic gene family.
Aruga J, Yozu A, Hayashizaki Y, Okazaki Y, Chapman VM, Mikoshiba K.
Gene 1996 Jun; 172(2):291.
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Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family.
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