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Last updated: 2016/11/27

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LNPEP polyclonal antibody

  • Catalog # : PAB25616
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of LNPEP.
  • Immunogen:
  • A synthetic peptide corresponding to 15 amino acids at C-terminus of human LNPEP.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 113
  • Reactivity:
  • Human
  • Specificity:
  • At least three isoforms are known to exist; this antibody will detect all three isoforms. Despite its predicted molecular weight, LNPEP often migrates at 165kD in SDS-PAGE.
  • Form:
  • Liquid
  • Purification:
  • Peptide affinity purification
  • Concentration:
  • 1 mg/mL
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of LNPEP in human lung tissue with LNPEP polyclonal antibody (Cat # PAB25616) at 1 ug/mL in (1) the absence and (2) the presence of blocking peptide.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4012
  • Gene Name:
  • LNPEP
  • Gene Alias:
  • CAP,IRAP,P-LAP,PLAP
  • Gene Description:
  • leucyl/cystinyl aminopeptidase
  • Gene Summary:
  • This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • AT (4) receptor,OTTHUMP00000196800,angiotensin IV receptor,insulin-regulated aminopeptidase,insulin-responsive aminopeptidase,otase,oxytocinase,placental leucine aminopeptidase,vasopressinase
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