LNPEP polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of LNPEP in human lung tissue with LNPEP polyclonal antibody (Cat # PAB25616) at 1 ug/mL in (1) the absence and (2) the presence of blocking peptide.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of LNPEP.
Immunogen
A synthetic peptide corresponding to 15 amino acids at C-terminus of human LNPEP.
Host
Rabbit
Theoretical MW (kDa)
113
Reactivity
Human
Specificity
At least three isoforms are known to exist; this antibody will detect all three isoforms. Despite its predicted molecular weight, LNPEP often migrates at 165kD in SDS-PAGE.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of LNPEP in human lung tissue with LNPEP polyclonal antibody (Cat # PAB25616) at 1 ug/mL in (1) the absence and (2) the presence of blocking peptide.Enzyme-linked Immunoabsorbent Assay
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Gene Info — LNPEP
Entrez GeneID
4012Protein Accession#
NP_005566Gene Name
LNPEP
Gene Alias
CAP, IRAP, P-LAP, PLAP
Gene Description
leucyl/cystinyl aminopeptidase
Omim ID
151300Gene Ontology
HyperlinkGene Summary
This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
AT (4) receptor|OTTHUMP00000196800|angiotensin IV receptor|insulin-regulated aminopeptidase|insulin-responsive aminopeptidase|otase|oxytocinase|placental leucine aminopeptidase|vasopressinase
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Interactome
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Pathway
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Disease
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