BAI1 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed, paraffin-embedded human brain, neurons tissue after heat-induced antigen retrieval.
Using BAI1 polyclonal antibody (Cat # PAB25591).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of BAI1.
Immunogen
A synthetic peptide corresponding to 16 amino acids at C-terminus of human BAI1.
Host
Rabbit
Reactivity
Bovine, Chicken, Hamster, Human, Monkey, Mouse, Rat
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (14 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed, paraffin-embedded human brain, neurons tissue after heat-induced antigen retrieval.
Using BAI1 polyclonal antibody (Cat # PAB25591). -
Gene Info — BAI1
Entrez GeneID
575Gene Name
BAI1
Gene Alias
FLJ41988
Gene Description
brain-specific angiogenesis inhibitor 1
Omim ID
602682Gene Ontology
HyperlinkGene Summary
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq
Other Designations
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Interactome
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Pathway
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