PCSK6 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed, paraffin-embedded human placenta (A) and human liver (B) tissue after heat-induced antigen retrieval.
Using PCSK6 polyclonal antibody (Cat # PAB25583).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PCSK6.
Immunogen
A synthetic peptide corresponding to 14 amino acids at Cys-rich motif (CRM) region of human PCSK6.
Host
Rabbit
Reactivity
Bovine, Horse, Human, Monkey, Rabbit, Rat
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed, paraffin-embedded human placenta (A) and human liver (B) tissue after heat-induced antigen retrieval.
Using PCSK6 polyclonal antibody (Cat # PAB25583).Enzyme-linked Immunoabsorbent Assay
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Gene Info — PCSK6
Entrez GeneID
5046Gene Name
PCSK6
Gene Alias
PACE4, SPC4
Gene Description
proprotein convertase subtilisin/kexin type 6
Omim ID
167405Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
paired basic amino acid cleaving system 4|subtilisin-like proprotein convertase 4|subtilisin-like protease|subtilisin/kexin-like protease PACE4
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Interactome
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Disease
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