HTR1B polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of HTR1B.
Immunogen
A synthetic peptide corresponding to 17 amino acids at internal region of human HTR1B.
Host
Rabbit
Reactivity
Human, Monkey
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed, paraffin-embedded human vessel (A) and human prostate (B) tissue after heat-induced antigen retrieval.
Using HTR1B polyclonal antibody (Cat # PAB25570). -
Gene Info — HTR1B
Entrez GeneID
3351Gene Name
HTR1B
Gene Alias
5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12
Gene Description
5-hydroxytryptamine (serotonin) receptor 1B
Omim ID
182131Gene Ontology
HyperlinkGene Summary
The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of 4 main groups, 5-HT-1, 5-HT-2, 5-HT-3, and 5-HT4, subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.[supplied by OMIM
Other Designations
OTTHUMP00000016769
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