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Last updated: 2017/7/16
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NPTX2 polyclonal antibody

  • Catalog # : PAB2556
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of NPTX2.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human NPTX2.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • Western Blot (1:1000)
    Immunohistochemistry (1:10-50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis of NPTX2 (arrow) using rabbit NPTX2 polyclonal antibody (Cat # PAB2556). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NPTX2 gene (Lane 2) (Origene Technologies).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human testis tissue reacted with NPTX2 polyclonal antibody (Cat # PAB2556) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 4885
  • Protein Accession#:
  • NP_002514;P47972
  • Gene Name:
  • NPTX2
  • Gene Alias:
  • NARP,NP-II,NP2
  • Gene Description:
  • neuronal pentraxin II
  • Gene Summary:
  • This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq
  • Other Designations:
  • apexin,neuronal activity-regulated pentaxin,pentraxin II
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