APLNR polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed, paraffin-embedded human brain, astrocyte tissue after heat-induced antigen retrieval.
Using APLNR polyclonal antibody (Cat # PAB25524).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of APLNR.
Immunogen
A synthetic peptide corresponding to 16 amino acids at 1st cytoplasmic domain of human APLNR.
Host
Rabbit
Reactivity
Hamster, Horse, Human
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-7 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed, paraffin-embedded human brain, astrocyte tissue after heat-induced antigen retrieval.
Using APLNR polyclonal antibody (Cat # PAB25524). -
Gene Info — APLNR
Entrez GeneID
187Gene Name
APLNR
Gene Alias
AGTRL1, APJ, APJR, FLJ90771, MGC45246
Gene Description
apelin receptor
Omim ID
600052Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq
Other Designations
APJ (apelin) receptor|angiotensin II receptor-like 1|angiotensin receptor-like 1
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Interactome
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Pathway
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Disease
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Publication Reference
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Apelin system detection in the reproductive apparatus of ewes grazing on semi-natural pasture.
Mercati F, Scocco P, Maranesi M, Acuti G, Petrucci L, Cocci P, Renzi A, De Felice E, Dall'Aglio C.
Theriogenology 2019 Nov; 139:156.
Application：IHC-P, Sheep, Ovary, Uterus.
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Apelin system detection in the reproductive apparatus of ewes grazing on semi-natural pasture.
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