ADRA1B polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed, paraffin-embedded human kidney, collecting duct tissue after heat-induced antigen retrieval.
Using ADRA1B polyclonal antibody (Cat # PAB25520).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ADRA1B.
Immunogen
A synthetic peptide corresponding to 16 amino acids at 1st cytoplasmic domain of human ADRA1B.
Host
Rabbit
Reactivity
Human, Monkey
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SLC22A3 (50%).
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (6 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed, paraffin-embedded human kidney, collecting duct tissue after heat-induced antigen retrieval.
Using ADRA1B polyclonal antibody (Cat # PAB25520). -
Gene Info — ADRA1B
Entrez GeneID
147Gene Name
ADRA1B
Gene Alias
ADRA1, ALPHA1BAR
Gene Description
adrenergic, alpha-1B-, receptor
Omim ID
104220Gene Ontology
HyperlinkGene Summary
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq
Other Designations
alpha-1B-adrenergic receptor
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Interactome
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Pathway
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Disease
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