AVPR1B polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed, paraffin-embedded human brain, pituitary tissue after heat-induced antigen retrieval.
Using AVPR1B polyclonal antibody (Cat # PAB25516).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of AVPR1B.
Immunogen
A synthetic peptide corresponding to 17 amino acids at N-terminal extracellular domain of human AVPR1B.
Host
Rabbit
Reactivity
Bovine, Dog, Horse, Human, Pig, Rabbit, Rat
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed, paraffin-embedded human brain, pituitary tissue after heat-induced antigen retrieval.
Using AVPR1B polyclonal antibody (Cat # PAB25516). -
Gene Info — AVPR1B
Entrez GeneID
553Gene Name
AVPR1B
Gene Alias
AVPR3
Gene Description
arginine vasopressin receptor 1B
Omim ID
600264Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq
Other Designations
OTTHUMP00000034344|antidiuretic hormone receptor 1B|arginine vasopressin receptor 3|pituitary vasopressin receptor 3|vasopressin V1B receptor
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Interactome
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Pathway
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Disease
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