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Last updated: 2017/12/10

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PHOX2A polyclonal antibody

  • Catalog # : PAB25492
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of PHOX2A.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human PHOX2A.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • PHOX2A antibody is predicted to not cross-react with other paired homeobox family members.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    Immunohistochemistry (2.5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of rat brain tissue lysate with PHOX2A polyclonal antibody (Cat # PAB25492) at 1 ug/mL in (1) the absence and (2) the presence of blocking peptide.
  • Immunohistochemistry
  • Immunohistochemistry
  • Immunohistochemical anyalysis of human brain tissue with PHOX2A polyclonal antibody (Cat # PAB25492) at 2.5 ug/mL.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 401
  • Gene Name:
  • PHOX2A
  • Gene Alias:
  • ARIX,CFEOM2,FEOM2,MGC52227,NCAM2,PMX2A
  • Gene Description:
  • paired-like homeobox 2a
  • Gene Summary:
  • The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq
  • Other Designations:
  • aristaless homeobox homolog,arix homeodomain protein
  • Related Disease
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