PHOX2A polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of rat brain tissue lysate with PHOX2A polyclonal antibody (Cat # PAB25492) at 1 ug/mL in (1) the absence and (2) the presence of blocking peptide.
Immunohistochemistry
Immunohistochemical anyalysis of human brain tissue with PHOX2A polyclonal antibody (Cat # PAB25492) at 2.5 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PHOX2A.
Immunogen
A synthetic peptide corresponding to C-terminus of human PHOX2A.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
PHOX2A antibody is predicted to not cross-react with other paired homeobox family members.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1 ug/mL)
Immunohistochemistry (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of rat brain tissue lysate with PHOX2A polyclonal antibody (Cat # PAB25492) at 1 ug/mL in (1) the absence and (2) the presence of blocking peptide.Immunohistochemistry
Immunohistochemical anyalysis of human brain tissue with PHOX2A polyclonal antibody (Cat # PAB25492) at 2.5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PHOX2A
Entrez GeneID
401Protein Accession#
NP_005160Gene Name
PHOX2A
Gene Alias
ARIX, CFEOM2, FEOM2, MGC52227, NCAM2, PMX2A
Gene Description
paired-like homeobox 2a
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq
Other Designations
aristaless homeobox homolog|arix homeodomain protein
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Interactome
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Disease
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