SDHD polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SDHD.
Immunogen
A synthetic peptide corresponding to internal region of human SDHD.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
At least three isoforms of THBS are known to exist; this antibody will detect all three.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
Immunocytochemistry (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of EL4 cell lysate with SDHD polyclonal antibody (Cat # PAB25486) at (1) 1 and (2) 2 ug/mL.Immunocytochemistry
Immunocytochemical anyalysis of EL4 cells with SDHD polyclonal antibody (Cat # PAB25486) at 2.5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SDHD
Entrez GeneID
6392Protein Accession#
NP_002993Gene Name
SDHD
Gene Alias
CBT1, PGL, PGL1, SDH4
Gene Description
succinate dehydrogenase complex, subunit D, integral membrane protein
Gene Ontology
HyperlinkGene Summary
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The subunit D protein is one of two integral membrane proteins anchoring the complex to the matrix side of the membrane. Mutations in SDHD have been linked to hereditary paraganglioma. [provided by RefSeq
Other Designations
succinate dehydrogenase complex, subunit D|succinate dehydrogenase ubiquinone cytochrome B small subunit
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Interactome
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Pathway
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Citrate cycle (TCA cycle)
- Metabolic pathways
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