ABCA7 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ABCA7.
Immunogen
A synthetic peptide corresponding to N-terminus of human ABCA7.
Host
Rabbit
Reactivity
Human
Specificity
ABCA7 antibody is human specific. At least two alternatively spliced transcript variants encoding distinct isoforms have been observed.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1-2 ug/mL)
Immunocytochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of 293 cell lysate with ABCA7 polyclonal antibody (Cat # PAB25479) at (1) 1 and (2) 2 ug/mL.Immunocytochemistry
Immunocytochemical anyalysis of 293 cells with ABCA7 polyclonal antibody (Cat # PAB25479) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ABCA7
Entrez GeneID
10347Protein Accession#
NP_061985Gene Name
ABCA7
Gene Alias
ABCA-SSN, ABCX, FLJ40025
Gene Description
ATP-binding cassette, sub-family A (ABC1), member 7
Omim ID
605414Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system. [provided by RefSeq
Other Designations
ATP-binding cassette, sub-family A, member 7|autoantigen SS-N|macrophage ABC transporter
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