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Last updated: 2016/12/4

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CHRM2 polyclonal antibody

  • Catalog # : PAB25473
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of CHRM2.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 352-364 at internal region of human CHRM2.
  • Sequence:
  • CQNGDEKQNIVARK
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 50
  • Reactivity:
  • Mouse
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:128000)
    Western Blot (0.5-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • CHRM2 polyclonal antibody (Cat # PAB25473) (2 ug/mL) staining of mouse brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1129
  • Gene Name:
  • CHRM2
  • Gene Alias:
  • FLJ43243,HM2,MGC120006,MGC120007
  • Gene Description:
  • cholinergic receptor, muscarinic 2
  • Gene Summary:
  • The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq
  • Other Designations:
  • 7TM receptor,cholinergic receptor, muscarinic 2, isoform a,muscarinic M2 receptor,muscarinic acetylcholine receptor M2
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