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Last updated: 2017/8/13

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FBL polyclonal antibody

  • Catalog # : PAB25471
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of FBL.
  • Immunogen:
  • A synthetic peptide corresponding to internal region of human FBL.
  • Sequence:
  • CKRVSISEGDDKIEYR
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 35
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • FBL polyclonal antibody (Cat # PAB25471) (1 ug/mL) staining of HEK293 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2091
  • Gene Name:
  • FBL
  • Gene Alias:
  • FIB,FLRN,RNU3IP1
  • Gene Description:
  • fibrillarin
  • Gene Summary:
  • This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq
  • Other Designations:
  • 34-kD nucleolar scleroderma antigen,RNA, U3 small nucleolar interacting protein 1
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