NR0B1 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of NROB1 (arrow) using rabbit NR0B1 polyclonal antibody (Cat # PAB2545). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NROB1 gene (Lane 2) (Origene Technologies).
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of NR0B1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human NR0B1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Transfected lysate)
Western blot analysis of NROB1 (arrow) using rabbit NR0B1 polyclonal antibody (Cat # PAB2545). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NROB1 gene (Lane 2) (Origene Technologies). -
Gene Info — NR0B1
Entrez GeneID
190Protein Accession#
NP_000466;P51843Gene Name
NR0B1
Gene Alias
AHC, AHCH, AHX, DAX-1, DAX1, DSS, GTD, HHG, NROB1
Gene Description
nuclear receptor subfamily 0, group B, member 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq
Other Designations
OTTHUMP00000023102|gonadotropin deficiency|nuclear hormone receptor
-
Interactome
-
Publication Reference
-
A novel mutation in DAX1 gene causing different phenotypes in three siblings with adrenal hypoplasia congenita.
Calliari LE, Longui CA, Rocha MN, Faria CD, Kochi C, Melo MR, Melo MB, Monte O.
Genetics and Molecular Research 2007 May; 6(2):277.
-
NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma.
Kinsey M, Smith R, Lessnick SL.
Molecular Cancer Research 2006 Nov; 4(11):851.
Application：WB-Tr, Human, TC71, EWS502, A673 cells.
-
A novel mutation in DAX1 gene causing different phenotypes in three siblings with adrenal hypoplasia congenita.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com