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Last updated: 2016/11/27

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KCNIP3 polyclonal antibody

  • Catalog # : PAB25439
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of KCNIP3.
  • Immunogen:
  • A synthetic peptide corresponding to N-terminus of human KCNIP3.
  • Sequence:
  • SLLGDLGHTPLSC
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 30
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize isoform 1 (NP_038462.1) only.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:1000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • HEK293 lysate (10 ug protein in RIPA buffer) overexpressing human KCNIP3 with C-terminal MYC tag probed with KCNIP3 polyclonal antibody (Cat # PAB25439) (1 ug/mL) in Lane 1 and probed with anti-MYC Tag (1/1000) in lane 3. Mock-transfected HEK293 probed with KCNIP3 polyclonal antibody (Cat # PAB25439) (1 mg/mL) in Lane 2. Primary incubations were for 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • KCNIP3
  • Gene Alias:
  • CSEN,DREAM,KCHIP3,MGC18289
  • Gene Description:
  • Kv channel interacting protein 3, calsenilin
  • Gene Summary:
  • This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
  • Other Designations:
  • A-type potassium channel modulatory protein 3,DRE-antagonist modulator,Kv channel interacting protein 3,calsenilin, presenilin-binding protein, EF hand transcription factor,potassium channel interacting protein 3
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