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QKI polyclonal antibody

  • Catalog # : PAB2543
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of QKI.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human QKI.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Recommend Usage:
  • Western Blot (1:1000)
    Immunohistochemistry (1:10-50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human brain tissue reacted with QKI polyclonal antibody (Cat # PAB2543) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 9444
  • Protein Accession#:
  • NP_996736;Q96PU8
  • Gene Name:
  • QKI
  • Gene Alias:
  • DKFZp586I0923,Hqk,QK,QK1,QK3
  • Gene Description:
  • quaking homolog, KH domain RNA binding (mouse)
  • Gene Summary:
  • QKI belongs to a family of RNA-binding proteins that have an HNRNPK (MIM 600712) homology (KH) domain embedded in a 200-amino acid region called the GSG domain. Other members of this family include SAM68 (KHDRBS1; MIM 602489) and SF1 (MIM 601516) (Chen and Richard, 1998 [PubMed 9671495]). QKI proteins regulate RNA splicing, export of target RNAs from the nucleus, translation of proteins, and RNA stability (Lauriat et al., 2008 [PubMed 17918747]).[supplied by OMIM
  • Other Designations:
  • OTTHUMP00000017581,OTTHUMP00000017582,OTTHUMP00000017583,RNA binding protein HQK,homolog of mouse quaking QKI (KH domain RNA binding protein),quaking homolog, KH domain RNA binding
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