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CAV1 (phospho Y14) polyclonal antibody

  • Catalog # : PAB25309
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of CAV1.
  • Immunogen:
  • Synthetic phosphopeptide corresponding to residues surrounding Y14 of human CAV1.
  • Sequence:
  • H-L-Yp-T-V
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity chromatography
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of extracts from NIH/3T3 cells, untreated or treated with H2O2, using CAV1 (phospho Y14) polyclonal antibody (Cat # PAB25309).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 857
  • Gene Name:
  • CAV1
  • Gene Alias:
  • BSCL3,CAV,CGL3,MSTP085,VIP21
  • Gene Description:
  • caveolin 1, caveolae protein, 22kDa
  • Gene Summary:
  • The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000025031,caveolae protein, 22-kD,caveolin 1,caveolin 1 caveolae protein, 22kD,caveolin 1, alpha isoform,caveolin 1, beta isoform,caveolin-1 beta isoform protein,cell growth-inhibiting protein 32
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