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PTK2 (phospho Y861) polyclonal antibody

  • Catalog # : PAB25279
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of PTK2.
  • Immunogen:
  • Synthetic phosphopeptide corresponding to residues surrounding Y861 of human PTK2.
  • Sequence:
  • H-I-Yp-Q-P
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 125
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity chromatography
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of extracts from HepG2, HeLa and 293 cells using PTK2 (phospho Y861) polyclonal antibody (Cat # PAB25279).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5747
  • Gene Name:
  • PTK2
  • Gene Alias:
  • FADK,FAK,FAK1,pp125FAK
  • Gene Description:
  • PTK2 protein tyrosine kinase 2
  • Gene Summary:
  • This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. [provided by RefSeq
  • Other Designations:
  • focal adhesion kinase 1
  • Interactome
  • Interactome
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