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Last updated: 2016/11/27

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HP polyclonal antibody

  • Catalog # : PAB25186
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of HP.
  • Immunogen:
  • A synthetic peptide corresponding to HP.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • HP polyclonal antibody detects endogenous levels of HP protein.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Immunohistochemistry (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human brain tissue using HP polyclonal antibody (Cat # PAB25186).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 3240
  • Gene Name:
  • HP
  • Gene Alias:
  • BP,HP2-ALPHA-2,HPA1S,MGC111141
  • Gene Description:
  • haptoglobin
  • Gene Summary:
  • This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • binding peptide,haptoglobin alpha(1S)-beta,haptoglobin alpha(2FS)-beta,haptoglobin, alpha polypeptide,haptoglobin, beta polypeptide
  • Related Disease
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