BMP8B polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human testis tissue using BMP8B polyclonal antibody (Cat # PAB25185).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of BMP8B.
Immunogen
A synthetic peptide corresponding to BMP8B.
Host
Rabbit
Reactivity
Human
Specificity
BMP8B polyclonal antibody detects endogenous levels of BMP8B protein.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human testis tissue using BMP8B polyclonal antibody (Cat # PAB25185). -
Gene Info — BMP8B
Entrez GeneID
656Gene Name
BMP8B
Gene Alias
BMP8, MGC131757, OP2
Gene Description
bone morphogenetic protein 8b
Omim ID
602284Gene Ontology
HyperlinkGene Summary
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity. [provided by RefSeq
Other Designations
OTTHUMP00000010836|bone morphogenetic protein 8 (osteogenic protein 2)|bone morphogenetic protein 8B|dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2))|osteogenic protein 2
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Interactome
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Pathway
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Disease
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Publication Reference
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Bone Morphogenetic Protein-8B Expression is Induced in Steatotic Hepatocytes and Promotes Hepatic Steatosis and Inflammation In Vitro.
Mahli A, Seitz T, Beckröge T, Freese K, Thasler WE, Benkert M, Dietrich P, Weiskirchen R, Bosserhoff A, Hellerbrand C.
Cells 2019 May; 8(5):E457.
Application：WB-Ce, WB-Tr, Human, Human hepatocytes.
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Bone Morphogenetic Protein-8B Expression is Induced in Steatotic Hepatocytes and Promotes Hepatic Steatosis and Inflammation In Vitro.
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