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Last updated: 2016/11/27

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BIRC7 polyclonal antibody

  • Catalog # : PAB25172
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of BIRC7.
  • Immunogen:
  • A synthetic peptide corresponding to BIRC7.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 21
  • Reactivity:
  • Human
  • Specificity:
  • BIRC7 polyclonal antibody detects endogenous levels of BIRC7 protein.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of COLO 205 cell lysate with BIRC7 polyclonal antibody (Cat # PAB25172).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • BIRC7
  • Gene Alias:
  • KIAP,LIVIN,ML-IAP,MLIAP,RNF50
  • Gene Description:
  • baculoviral IAP repeat-containing 7
  • Gene Summary:
  • The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000031536,OTTHUMP00000031537,baculoviral IAP repeat-containing protein 7,kidney inhibitor of apoptosis protein,livin inhibitor of apoptosis,livin inhibitor-of-apoptosis,melanoma inhibitor of apoptosis protein
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