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Last updated: 2016/11/27

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MNDA polyclonal antibody

  • Catalog # : PAB25135
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of MNDA.
  • Immunogen:
  • A synthetic peptide corresponding to MNDA.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 46
  • Reactivity:
  • Human
  • Specificity:
  • MNDA polyclonal antibody detects endogenous levels of MNDA protein.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of LoVo cell lysate with MNDA polyclonal antibody (Cat # PAB25135).
  • Immunohistochemistry
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry
  • Gene Information
  • Entrez GeneID:
  • 4332
  • Gene Name:
  • MNDA
  • Gene Alias:
  • PYHIN3
  • Gene Description:
  • myeloid cell nuclear differentiation antigen
  • Gene Summary:
  • The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000024384
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