MNDA polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of LoVo cell lysate with MNDA polyclonal antibody (Cat # PAB25135).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MNDA.
Immunogen
A synthetic peptide corresponding to MNDA.
Host
Rabbit
Theoretical MW (kDa)
46
Reactivity
Human
Specificity
MNDA polyclonal antibody detects endogenous levels of MNDA protein.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of LoVo cell lysate with MNDA polyclonal antibody (Cat # PAB25135).Immunohistochemistry
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Gene Info — MNDA
Entrez GeneID
4332Gene Name
MNDA
Gene Alias
PYHIN3
Gene Description
myeloid cell nuclear differentiation antigen
Omim ID
159553Gene Ontology
HyperlinkGene Summary
The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq
Other Designations
OTTHUMP00000024384
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Interactome
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Disease
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