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ABCD1 polyclonal antibody

  • Catalog # : PAB25128
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ABCD1.
  • Immunogen:
  • A synthetic peptide corresponding to ABCD1.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 75
  • Reactivity:
  • Human
  • Specificity:
  • ABCD1 polyclonal antibody detects endogenous levels of ABCD1 protein.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of Jurkat cell lysate with ABCD1 polyclonal antibody (Cat # PAB25128).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 215
  • Gene Name:
  • ABCD1
  • Gene Alias:
  • ABC42,ALD,ALDP,AMN
  • Gene Description:
  • ATP-binding cassette, sub-family D (ALD), member 1
  • Gene Summary:
  • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000025960,adrenoleukodystrophy protein
  • Gene Pathway
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