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CTTN polyclonal antibody

  • Catalog # : PAB25120
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CTTN.
  • Immunogen:
  • A synthetic peptide corresponding to CTTN.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 80
  • Reactivity:
  • Human
  • Specificity:
  • CTTN polyclonal antibody detects endogenous levels of CTTN protein.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of HeLa cell lysate with CTTN polyclonal antibody (Cat # PAB25120).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 2017
  • Gene Name:
  • CTTN
  • Gene Alias:
  • EMS1,FLJ34459
  • Gene Description:
  • cortactin
  • Gene Summary:
  • This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Two splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • 1110020L01Rik,ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate),oncogene EMS1
  • Interactome
  • Interactome
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