CYP7B1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of LoVo cell lysate with CYP7B1 polyclonal antibody (Cat # PAB25096).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue using CYP7B1 polyclonal antibody (Cat # PAB25096).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CYP7B1.
Immunogen
A synthetic peptide corresponding to CYP7B1.
Host
Rabbit
Theoretical MW (kDa)
58
Reactivity
Human
Specificity
CYP7B1 polyclonal antibody detects endogenous levels of CYP7B1 protein.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of LoVo cell lysate with CYP7B1 polyclonal antibody (Cat # PAB25096).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue using CYP7B1 polyclonal antibody (Cat # PAB25096). -
Gene Info — CYP7B1
Entrez GeneID
9420Gene Name
CYP7B1
Gene Alias
CBAS3, CP7B, SPG5A
Gene Description
cytochrome P450, family 7, subfamily B, polypeptide 1
Omim ID
603711Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. [provided by RefSeq
Other Designations
cytochrome P450, subfamily VIIB (oxysterol 7 alpha-hydroxylase), polypeptide 1|oxysterol 7alpha-hydroxylase
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Interactome
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