CASP2 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HUVEC cell lysate treated with Adriamycin 05uM 4h with CASP2 polyclonal antibody (Cat # PAB25093).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using CASP2 polyclonal antibody (Cat # PAB25093).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CASP2.
Immunogen
A synthetic peptide corresponding to CASP2.
Host
Rabbit
Theoretical MW (kDa)
51
Reactivity
Human
Specificity
CASP2 polyclonal antibody detects endogenous levels of CASP2 protein.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HUVEC cell lysate treated with Adriamycin 05uM 4h with CASP2 polyclonal antibody (Cat # PAB25093).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using CASP2 polyclonal antibody (Cat # PAB25093). -
Gene Info — CASP2
Entrez GeneID
835Gene Name
CASP2
Gene Alias
CASP-2, ICH-1L, ICH-1L/1S, ICH1, NEDD2
Gene Description
caspase 2, apoptosis-related cysteine peptidase
Omim ID
600639Gene Ontology
HyperlinkGene Summary
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq
Other Designations
ICH-1 protease|NEDD2 apoptosis regulatory|caspase 2|neural precursor cell expressed, developmentally down-regulated 2
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Interactome
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Disease
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