FGL2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FGL2.
Immunogen
A synthetic peptide corresponding to amino acids 6-60 of human FGL2.
Host
Rabbit
Theoretical MW (kDa)
50
Reactivity
Human
Specificity
FGL2 polyclonal antibody detects endogenous levels of FGL2 protein.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of 293 cell lysate treated with insulin with FGL2 polyclonal antibody (Cat # PAB25089). -
Gene Info — FGL2
Entrez GeneID
10875Protein Accession#
Q14314Gene Name
FGL2
Gene Alias
T49, pT49
Gene Description
fibrinogen-like 2
Omim ID
605351Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites. [provided by RefSeq
Other Designations
fibrinogen-like protein 2|fibroleukin
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Interactome
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Disease
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Publication Reference
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Regulatory T cells induce polarization of pro-repair macrophages by secreting sFGL2 into the endometriotic milieu.
Xin-Xin Hou, Xiao-Qiu Wang, Wen-Jie Zhou, Da-Jin Li.
Communications Biology 2021 Apr; 4(1):499.
Application:IHC-P, Human, Human endometrium and ectopic lesions.
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Regulatory T cells induce polarization of pro-repair macrophages by secreting sFGL2 into the endometriotic milieu.
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